cartouche ECN WORKSHOP
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Abstracts

2023 - Poster

Therapeutics-Miscellaneous

Treatment of gout patients in seven primary care centers from Barcelona

Cesar Diaz-Torne (1), Daniel Martinez-Laguna (2), Raquel Gayarre (3), Meritxell Aivar (4), Jordi Hoyo (5), Angeles Conesa (2), Carlen Reyes (6), Cristina Carbonell (7), Jose Luis Estebanez (8), Maria Antonia Pou (3)

2023 - Oral communication

Mechanisms of Calcification

Ex vivo reversion and inhibition of calcification using therapeutic nanoparticular formulations

Franziska Linss (1), Jacqueline Bodes (1), Dennis Mulac (1), Klaus Langer (1), Anja Feldmann (2), Yvonne Nitschke (2), Frank Rutsch (2)

2023 - Poster

Rare diseases

Zebrafish models to study ectopic calcification and calcium associated pathologies

João M.A. Santos (1), Vincent Laizé (1), Paulo J. Gavaia (1,2), Natércia Conceição (1,2), M. Leonor Cancela (1,2)

2023 - Oral communication

OA-Genetics and EUROGOUT-Inflammation

Sex and ethnicity-stratified analyses of gout comorbidities and gout genetic risk in the uk biobank and all of us cohorts

Nicholas A Sumpter, Murray J Cadzow, Riku Takei, Megan P Leask, Angelo Gaffo, Alexander So, Richard J Reynolds, Tony R Merriman

2023 - Oral communication

Rare diseases

Unravelling the basic calcium phosphate crystal-dependent chondrocyte protein secretome; a role for TGF-β signaling

Roderick H.M.J Stassen, Guus G.H. Van Den Akker, Don A.M Surtel, Andy Cremers, Mandy J. Peffers, Marjolein M.C. Caron, Lodewijk W. Van Rhijn, Tim J.M. Welting

2023 - Poster

Mechanisms-Epidemiology

Which is the most appropriate sonographic definition for asymptomatic hyperuricemia with MSU crystal deposits?

Peral-Garrido Ml, Gómez Sabater S, Caño Alameda R, Bermúdez García S, Lozano Palencia Mt Sánchez Ortiga R Perdiguero Gil M, Caro Martínez E, Ruiz García C, Francés R, Pascual E, Andrés M.

2023 - Oral communication

Therapeutics-Miscellaneous

Real-life results of urate-driven pharmacotherapy with three urate lowering drugs in gout: allopurinol, febuxostat and benzbromarone

Hotea I. (1,2), Giesen T. (1), Comarniceanu A. (1), Efde M. (1), Van Osch F. (3), Janssen M. (1), Jansen Tltha (1,4).

2023 - Oral communication

Mechanisms of Calcification

Effects of de novo calcification in a new ex-vivo human model of osteoarthritis

Elodie Faure, Julien Wegrzyn (2), Ilaria Bernabei (1), Nicolas Bertheaume (3), Tristan Pascart (3), Thomas Hugle (1), Nathalie Busso (1), Sonia Nasi (1)

2023 - Oral communication

Therapeutics-Miscellaneous

Rationale and design for PODAGRA II: a multicenter randomized phase 2/3 study assessing the efficacy and safety of dapansutrile, an orally administered specific inhibitor of the NLRP3 inflammasome in subjects with an acute gout flare

Tim Jansen, Phil Piscitelli, Cynthia Barrow, Kip Vought, Amy Poshusta, Heather Kapushoc, Andrea Leonard-Segal, Mustafa Noor, Damaris Skouras, Charles Dinarello, Naomi Schlesinger

2023 - Oral communication

Mechanisms-Epidemiology

Hyperuricemia is associated with coronary artery atherosclerosis in men: results from the SCAPIS study

Panagiota Drivelegka (1), Helena Forsblad-D’Elia (1), Göran Bergström (2,3), Erika Fagman (4,5), Lennart Th Jacobsson (1), Mats Dehlin (1)

2023 - Poster

Mechanisms-Epidemiology

Alterations in lipidome profiles distinguish early-onset hyperuricemia, gout, and the effect of urate-lowering treatment

Blanka Stibůrková (1,2), Kateřina Pavelcová (1), Jana Mašínová (1), Lenka Hasikova (1), Karel Pavelka (1), Aleš Kvasnička (3,4, David Friedecký (3,4, Radana Brumarová (3,4), Markéta Pavlíková (5)

2023 - Poster

Mechanisms-Epidemiology

Diagnosis of gout in electronic primary care medical records

Cesar Diaz-Torne (1), Daniel Martinez-Laguna (2), Jose Luis Estebanez (3), Angeles Conesa (2), Jordi Hoyo (4) , Cristina Carbonell (5), Meritxell Aivar (6), Carlen Reyes (7), Raquel Gayarre (8), Maria Antonia Pou (8)

2023 - Oral communication

Mechanisms of Calcification

Similar histological calcium crystal deposition in osteoarthritis and chondrocalcinosis

Sina Stücker, Franziska Kosslowski, Christoph H. Lohmann, Jessica Bertrand

2023 - Poster

OA-Genetics and EUROGOUT-Inflammation

Transcriptomic analysis of peripheral blood mononuclear cells in gout and hyperuricemia

Valentin Nica, Georgiana Cabău, Orsolya Gaal, Medeea Badii, Andreea-Manuela Mirea, Ioana Hotea, Hint Consortium, Cristina Pamfil, Simona Rednic, Radu A. Popp, Tania O. Crișan, Leo A.B. Joosten

2023 - Oral communication

Rare diseases

Altered transcription activity in gout reveals new genetic targets for msu crystal-dependent inflammation

Richard J Reynolds, Megan Leask, Nicholas Sumpter, Tony R Merriman, Pariyaphon Lertprachakwong, Jeffrey C Edberg.

2023 - Poster

Mechanisms-Epidemiology

Antinuclear antibodies in gout: the new vomit (victims of modern immunology techniques)

Ana Maria Herrero-Beites, Cristina Vázquez-Puente, Maria Del Consuelo Modesto-Caballero, Fernando Pérez-Ruiz

2023 - Oral communication

Mechanisms of Calcification

Sortilin is associated with cartilage calcification in osteoarthritis

Elisabeth Richter, Christoph Lohmann, Claudia Goettsch, Francesco Dell’Accio, Jessica Bertrand

2023 - Poster

Rare diseases

Investigator-initiated pilot study evaluating the efficacy of Etanercept in acute gout flare

Naomi Schlesinger, Md, Dirk F. Moore, Phd, Sir Marc Feldmann AC, MB BS, PHD, FRCPATH, FRCP

2023 - Oral communication

Rare diseases

Genetic and physiological effects of insulin-like growth factor-1 (IGF-1) on human urate homeostasis

David B. Mount, Megan P. Leask, Tony Merriman, Asim Mandal

2023 - Oral communication

OA-Genetics and EUROGOUT-Inflammation

Evidence for causality of diacylglycerol, glutamine, and androsterone sulfate for gout

Riku Takei, Nicholas A. Sumpter, Megan P. Leask, Tony R. Merriman

2023 - Oral communication

OA-Genetics and EUROGOUT-Inflammation

Investigating circadian mechanisms in the immune response to monosodium urate crystals

Megan Leask, Nicholas Sumpter, Ayona Roychowdhury, Karen L Gamble, Pariyaphon Lertprachakwong, Tony R Merriman, Jeffrey C Edberg and Richard Reynolds

2023 - Poster

Mechanisms of Calcification

The nomenclature of calcium pyrophosphate deposition (CPPD) disease – results of a systematic literature review for the gout, hyperuricemia and crystal-associated disease network (G-CAN) CPPD nomenclature project

Silvia Sirotti, Edoardo Cipolletta, Charlotte Jauffret, Enrico Cumbo, Emilio Filippucci, Tristan Pascart, Sara K. Tedeschi, Robert Terkeltaub, Nicola Dalbeth, Georgios Filippou

2023 - Oral communication

Therapeutics-Miscellaneous

Impact of combined intervention with clinical nurse specialist in the management of cardiovascular risk in patients with gout

Calvo-Aranda E, Novella-Navarro M, Angel-Sesmero JA, Cardoso-Peñafiel P, Gomez-Gonzalez CM, Cebrian-Mendez L, Marin-Huertas C, Matias De La Mano Ma, Lojo-Oliveira L, Sanz-Jardon M, Sanchez-Aranda Fm, Navio-Marco MT

2023 - Oral communication

Therapeutics-Miscellaneous

Factors associated to loss for follow-up in a prospective gout cohort

Fernando Perez-Ruiz, Cristina Vazquez-Puente, Maria Del Consuelo Modesto- Caballero, Ana María Herrero-Beites

2023 - Poster

Mechanisms of Calcification

TGF-Β enhances phosphate-driven mineralization of human oa articular chondrocytes

Roderick H.M., J Stassen, Guus G.H. Van Den Akker, Don A.M Surtel, Andy Cremers, Marjolein M.C. Caron, Lodewijk W. Van Rhijn, Tim J.M. Welting